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Organic compounds that contain an aromatic ring with one or more hydrogen atoms replaced by a halogen atom; also known as haloarene or halogenoarene. Halogen atoms include bromine, chlorine, fluorine, iodine.
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Iodo-PEG7-alcohol is a PEG-based PROTAC linker utilized in the synthesis of Proteolysis-Targeting Chimeras (PROTACs). PROTACs are designed to harness the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
Used in the synthesis of PROTACs
PROTACs contain two different ligands connected by a linker
One ligand is for an E3 ubiquitin ligase
The other ligand is for the target protein
Exploits the intracellular ubiquitin-proteasome system
Selectively degrades target proteins
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5-Iodo-dCTP is a bioactive deoxynucleotide analog known to modulate nucleotide metabolism by interfering with specific aspects of DNA synthesis Through incorporation into nucleic acids it disrupts normal DNA replication processes allowing detailed exploration of nucleotide biosynthesis pathways Experimentally 5-Iodo-dCTP serves as a molecular tool to probe polymerase enzyme function and analyze mechanisms underlying DNA synthesis fidelity It is commonly employed in molecular biology investigations facilitating studies on disease-associated disruptions in nucleic acid metabolism
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2-Iodopyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors.
Biochemical reagent
Can be used as a biological material or organic compound
Used for life science related research
Reagent for preparing human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors
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